Florium

Florium

Once-daily, three-pronged oral therapy for the effective treatment of polymicrobial vaginal infections

Florium is an aptly selected single-day oral combination therapy for complete treatment of vaginal discharge syndromes. It act synergistically marries Fluconazole’s antifungal, Azithromycin’s antibacterial, and Secnidazole’s antiprotozoal activities into a brief one-dose regimen.

In treating Candida, Trichomonas, and other bacterial infections, Florium provides broad-spectrum coverage, rapid resolution of symptoms, and fewer recurrences in a single dose. Thus, it is extremely effective in the case of mixed or recurrent vaginities and, with better compliance, even more than multi-drug treatment regimens.

 

✅ Mechanism of Action – Synergistic Anti-Infective Therapy

Fluconazole (150 mg)

• Azole class of antifungal
• Blocks fungal cytochrome P450-dependent enzymes
• Active against Candida albicans and other yeasts
• Reduces recurrence of fungal vaginitis

Azithromycin (1 g)

• Macrolide broad-spectrum antibiotic
• binds to the 50S ribosomal subunit and stops bacterial protein synthesis
• Active against Chlamydia trachomatis and other Gram-positive/Gram-negative bacteria
• Enhances cure of sexually transmitted bacterial co-infections
  

Secnidazole (1 g)

• Long-acting nitroimidazole derivative
• Dissees DNA structure of anaerobic bacteria and protozoa
• Active against Trichomonas vaginalis, Gardnerella vaginalis, and anaerobes
• Offers prolonged post-treatment activity owing to prolonged half-life

📊 Therapeutic Targeting Table

Component	Pathogen/Condition	Clinical Indication
Fluconazole	Candida albicans	Fungal vaginitis treatment and prevention of recurrences
Azithromycin	Chlamydia trachomatis, bacterial STIs	Eliminates bacterial coinfections
Secnidazole	Trichomonas vaginalis, Gardnerella vaginalis	Trichomonas vaginalis, Gardnerella vaginalis

 

✅ Clinical Advantages of Florium

• Polymicrobial Targeting

1. 1. • Cures single regimen of bacterial, fungal, and protozoal infection.
        

• Single-Day, Patient-Friendly Regimen

1. • Increases compliance with single oral dosing.

• Broad-Spectrum Coverage

1. 1. • Extended coverage against Candida, Trichomonas, and mixed bacteria infections.
        

• Reduced Recurrence & Resistance Risk

1. • Combination blocks pathogen survival that frequently induces relapse.

• Improved Reproductive Health Outcomes

1. • By addressing infections early, Florium decreases risks of pelvic inflammatory disease and infertility due to untreated STIs or vaginosis.

✅ Indications

• Polymicrobial vaginal discharge syndromes 
• Fungal vaginitis (Candida)
• Trichomoniasis (Trichomonas vaginalis)
• Bacterial vaginosis (Gardnerella vaginalis, anaerobes)
• Mixed or recurrent vaginal infections 
• Syndromic management in gynecologic practice

✅ Dosage

• Florium Kit: Composed of Fluconazole 150 mg, Azithromycin 1 g, and Secnidazole 1 g. 
• Administration: All orally administered tablets on a given day, as advised by the gynecologist.

⚠️ Note:
Florium is a prescription-only therapy. It should not replace clinical consultation. Always follow your gynecologist’s guidance for use, especially in cases of pregnancy, lactation, liver disease, or drug hypersensitivity.

 

Schedule Prescription Drug-Caution:
Not sold by the retail without the prescription of a registered medical practitioner