Bactronil CV

Bactronil-CV
A two-in-one antibiotic combination with microbiome supplement for effective treatment of resistant bacterial infections

Bactronil-CV is a special formulation of Amoxycillin, a broad-spectrum penicillin-type antibiotic, and Clavulanic Acid, a β-lactamase inhibitor, specifically developed to bypass resistance in bacteria and ensure better infection control. Both were specifically chosen for their multi-pathway mechanism of action—Amoxycillin kills bacteria by preventing them from building their cell walls, and Clavulanic Acid prevents it from being made useless by β-lactamase enzymes, thus augmenting its antibacterial action.

For vaginal and intestinal microbiota supplementation with antibiotic therapy, Bactronil-CV can be co-administered with Lactobacillus (adjunct probiotic). Lactobacillus can restore defensive flora, diminishes antibiotic-associated diarrhea frequency, and may potentially reduce post-antibiotic candidal superinfection.

Bactronil-CV is formulated to be most useful in the treatment of moderate to severe infections, recurrent infections, or those caused by resistant organisms. It is especially well suited for respiratory, urinary, skin, dental, and polymicrobial infections, ensuring faster clinical recovery.

 

✅ Mechanism of Action – Synergistic Antibacterial Action + Microbiome Support

Amoxycillin

• Semi-synthetic penicillin with Gram positive and Gram negative spectrum
• Inhibits the construction of bacterial cell wall → death and lysis of the bacteria
• Is very effective in clearing the infection soon

Clavulanic Acid

• β-lactamase inhibitor, has no intrinsic antibacterial activity
• It protects amoxicillin from enzyme breakdown
• Broadens its antibacterial spectrum against resistant bacteria

Lactobacillus (Probiotic Adjunct)

• Recolonize healthy gut and urogenital tract flora
• Lactic acid and bacteriocins production → inhibitory to pathogenic microorganisms
• Reduces incidence of antibiotic associated diarrhea and overgrowth of treated yeast
• Provides a natural mucosal barrier and immune modulation

✅ Clinical Benefits of Bactronil-CV (+ Lactobacillus)

Broad Spectrum Coverage
 Active against Gram-positive, Gram-negative bacteria (including β-lactamase producing bacteria).

Effective in Resistant Infections
 Has clinical efficacy when normal penicillins or cephalosporins are ineffective.

Effective in Polymicrobial Infections
 Includes mixed bacterial flora, especially in many respiratory and dental infections.

More Rapid Recovery & Symptom Relief
 Decreases fever, pain and bacterial load more efficiently. 

Microbiome Protection with Lactobacillus
 Adjunct reduces GI side effects (e.g., antibiotic-associated diarrhea), supports flora balance, and may lower post-antibiotic candidiasis.

Multiple Formulations
 Available as tablets and suspensions—suitable for both adults and children.

Safe & Tolerated
 Well-established safety profile when taken as prescribed.

📊 Table: Standard Amoxycillin vs. Bactronil-CV ± Lactobacillus

Feature	Amoxycillin Alone	Bactronil-CV (Amoxycillin + Clavulanic Acid)	Bactronil-CV + Lactobacillus (Adjunct)
Spectrum	Narrower; resistance common	Extended spectrum; β-lactamase coverage	Same extended spectrum
Resistance Protection	None	Protected by clavulanic acid	Same protection
GI Tolerability	Baseline	Baseline	Improved; lower risk of AAD
Microbiome Impact	Greater disruption	Moderate disruption	Restoration of beneficial flora
Candidiasis Risk	Higher post-antibiotic	Moderate	Potentially reduced
Best Use	Mild infections, known sensitivity	Moderate–severe/resistant/polymicrobial	When tolerability & flora support desired

AAD = antibiotic-associated diarrhea.

✅ Indications

• Respiratory tract infections (sinusitis, bronchitis, pneumonia, tonsillitis, otitis media)
• Urinary tract infections (UTIs)
• Skin & soft tissue infections (cellulitis, wound infections, diabetic foot infections)
• Bone & joint infections
• Dental abscesses & oral infections
• Animal bite wounds
• Mixed or resistant bacterial infections

Lactobacillus adjunct is particularly helpful when there is a history of antibiotic-associated diarrhea, prior post-antibiotic thrush, or prolonged antibiotic courses.

✅ Dosage

Bactronil-CV (Antibiotic)

• Adults: 625 mg – 1 g twice a day, with food (as directed)
• Children: Weight-based dosing as oral suspension
• Duration: 5–14 days according to infection severity
• Important: Finish the full treatment to avoid resistance and relapse

Lactobacillus (Probiotic Adjunct)

• Common strength: 1–5 billion CFU once or twice a day (according to product label)
• Timing: Take 2–3 hours apart from antibiotic dosage
• Duration: Throughout antibiotic treatment and continue 7–14 days after stopping
• Storage: Follow label—refrigeration is necessary for some strains; others are shelf-stable

⚠️ Precautions (Lactobacillus)

• Use with caution in patients with severe immunocompromise, central venous catheter, or critical illness—consult prescriber.
• Discontinue and seek consultation if persistent GI symptoms or infection signs develop.

Schedule Prescription Drug-Caution:
Not sold by the retail without the prescription of a registered medical practitioner