Calmsol MD

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Calmsol MD is a combination drug that contains mefenamic acid (250 mg) and Drotaverine hydrochloride (80 mg), designed to provide effective relief from various types of pain. Mefenamic acid is a nonsteroidal anti-inflammatory drug (NSAID) that helps reduce inflammation and pain, while Drotaverine is a muscle relaxation that relieves smooth muscle cramps. Mainly used as a pain reliever, it is effective in treating menstrual cramps, abdominal pain, muscle cramps, and other spasmodic pain conditions.

Salt consumption
Mefenamic Acid 250 mg + Drotaverine Hydrochloride 80 mg Tab

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Advanced Dual-Action Formula for Inflammation & Muscle Spasms

Calmsol MD is a scientifically formulated combination drug that should rapidly and effectively stop pain and muscle spasms related to both inflammatory conditions, and smooth muscle conditions. Calmsol MD is comprised of 250 mg of Mefenamic Acid (an NSAID which is clinically proven) and 80 mg of Drotaverine Hydrochloride (a potent antispasmodic).

This double action addresses inflammatory pain and muscle cramps at the same time, which makes Calmsol MD very suitable for dysmenorrhea, GI or urinary colic pain, postoperative pain, renal or biliary spasms. It is a dependable substitute for regimens that employ multiple drugs and is particularly useful to women for pregnancy-related uterine cramps with medical authorization.

💊 Expanded Composition Table – Calmsol MD (perTablet)

Active Ingredient

Quantity

Pharmacological Class

Mechanism of Action

Clinical Function

Mefenamic Acid

250 mg

NSAID (Non-Steroidal Anti-Inflammatory Drug) 

Inhibits cyclooxygenases (COX-1 and COX-2) → reduces production of prostaglandins 

Reduces inflammation, pain and fever when associated with menstrual cramp, colic and muscular pain.

Drotaverine Hydrochloride

80 mg

Antispasmodic (PDE-4 Inhibitor) 

Inhibits phosphodiesterase-4 → increases cAMP → relaxes smooth muscle under the influence of pharmacological agents 

Relaxes smooth muscle spasms in gastrointestinal tract, uterus, kidneys, biliary ducts and urinary tract (not affordable in bladder and urinary function) 

🧪 Pharmacodynamic Synergy

Combination Effect

Mechanism

Clinical Advantage

Mefenamic Acid + Drotaverine

Combines anti-inflammatory plus muscle-relaxant effects 

Provides complete pain and cramps relief in one medication ideal for spasmodic inflammatory pain

 

Mefenamic acid addresses the pain at its source while drotaverine relaxes the muscle constricted by the spasm

Reduces polypharmacy, improves patient compliance and enhances clinical outcomes

🩺 Calmsol MD Therapeutic Benefits

1. Dual-Action Relief
Calmsol MD has both anti-inflammatory and antispasmodic action that can offer pain relief in a single tablet.

2. Fast Actingeneural
Calmsol MD works quickly to provide relief and comfort for patients.


3. Range of Indications
Calmsol MD works on multiple types of pain: 

  • Menstrual cramps (dysmenorrhea)
  • Abdominal colic
  • Renal & biliary colic 
  • Spasms in the gastrointestinal or urinary tract
  • Post-operative or post-traumatic pain
  • Muscle headaches

4. Pregnancy Safety (with Supervision)
Drotaverine has been widely used during early pregnancy to help manage uterine spasms and is safer than many other NSAIDs, including Ibuprofen, offering relief to patients without negatively impacting maternal health when taken under supervision.

5. Reduced need for Polypharmacy 
One unit dose covers both the spastic and inflammatory aspects–reducing the need for multiple pain medications and improving pill burden.

6. Improves Quality of Life
By providing effective clinical management of both pain and cramps, Calmsol MD improves the ability of patients to perform daily activities, mobility and quality of life.

7. Acceptable & Safe
Calmsol MD has generally been found to be well-tolerated with respect to safety; side effects are generally mild to moderate and safely managed under standard treatment regimens.

Calmsol MD

📦Indications:

  • Menstrual cramps (Dysmenorrhea)
  • Spasms of the GI tract or urinary tract
  • Renal colic / Biliary colic
  • Post-op pain
  • Myofascial tension headaches
  • Uterine cramps in early pregnancy (under the guidance of a physician)

🔬Why Calmsol MD?

  •  Pain control via dual mechanisms
  •  Works quickly and lasts longer than conventional meds
  •  Has historically been used in pregnancy for uterine spasm
  • Decrease in the number of meds taken for acute and chronic cramps
  •  Quick, easy, and effective for acute and chronic cramps
  •  combination of effects provide few GI side effects when medication is taken with food

⚠️Side effects (potential, not common);

  • nausea, vomiting
  • Bloating, discomfort in the abdomen
  • Dizziness, headache
  • dry mouth, drowsiness 
  • Heartburn, indigestion
  • diarrhea or constipation
  • palpitations or slight drop in BP 
  • sweating or fatigue
  • skin allergies or rashes 
  • rare: GI bleeding, ulcers, renal or liver dysfunction
  • Serious allergic reactions (swelling, difficulty breathing- Seek emergency medical help)

🚨 Warnings & Precautions

  • Do not use if you are allergic to NSAIDS, Mefenamic Acid or Drotaverine.
  • Use with caution in patients with ulcers, liver disease, renal disease, or heart disease 
  • Not for use as long-term solution without supervision from a physician 
  • Take medication after meals to minimize the risk for gastric irritation 
  • Avoid alcohol; may increase the risk of gastric irritation 
  • Safe in pregnancy and has been used for some uterine spasms under the guidance of a physician (especially in the first trimester) 
  • Use caution when driving or operating dangerous equipment; there may be effects such as drowsiness or dizziness.

💬 Calmsol MD – Dual-Relief Therapy That Works When You Need It Most

Powerful, fast, and trusted—Calmsol MD is your one-stop solution for pain and cramps.
Ask your physician today about Calmsol MD.

FAQ's

Que. Calmsol is used for MD?
Ans. Calmsol MD is used to relieve diverse kinds of ache, such as menstrual cramps, stomach ache, colic and muscle spasms. It combines anti -inflammatory and antispasmodic moves.

Que. Is Calmsol MD secure at some point of being pregnant?
Ans. Yes, Calmsol MD is commonly taken into consideration secure for the duration of early pregnancy while used beneath scientific supervision. However, it ought to be postponed in the 1/3 trimester unless the physician is advised.

Que. How ought to I take Calmsol Md?
Ans. Take the Calmsol MD prescribed by using your physician properly, usually after food to lessen stomach pain. Do now not exceed the encouraged dose.

Que. Can Calmsol MD reason about consequences?
Ans. Some human beings can also enjoy nausea, dizziness, stomach disillusioned or dry mouth. Severe facet outcomes are rare, but are viable with extended use or overdose.

Que. Can I take Calmsol Md with other drugs?
Ans. Consult your physician earlier than combining Calmsol MD with different pills, mainly blood thin, diuretics, or other NSAIDs to avoid interplay.

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